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CENTRAL TOLERANCE
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DeCS
Descriptor
English
:
Central Tolerance
Descriptor
Spanish
:
Tolerancia Central
Descriptor
Portuguese
:
Tolerāncia Central
Tree Number:
G12.425.746.425.800.200
Definition
English
:
The mechanism, in central lymphoid organs (THYMUS;
BONE MARROW
), that prevents immature
lymphocytes
from reacting to SELF-ANTIGENS. This is accomplished by
CLONAL ANERGY
and
CLONAL DELETION.
History Note
English
:
2012
Allowable Qualifiers
English
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
54818
Unique Identifier:
D061167
Occurrence in VHL
:
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DeCS
CID-10
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